Sergio Mannino graduated in Architecture from the University of Florence, Italy under the direction of Ettore Sottsass and Remo Buti. He collaborated for 3 years with Professor Remo Buti during which time he had the opportunity to study furniture design and interior architecture in depth.

In September 2002 he mounted a one-man show of his furniture designs, including 9 built-pieces and 100 watercolors, at the Memphis-Postdesign Gallery in Milan, once again under Sottsass' supervision.

A collaboration with Dutch designer Jan Habraken produced the ooo! lamp, presented in 2008 and distinguished as I.D. Magazine Product of the Week and as Best Pick of the ICFF by Metropolis.